Professore ordinario
Settore scientifico disciplinare:
Chimica e biotecnologia delle fermentazioni (CHIM/11)
  • U04, Piano: 4, Stanza: 4032


Prof. Paola Branduardi BSc PhD, Full Professor in Chemistry of Fermentation and Industrial Microbiology at the University of Milano-Bicocca (Italy).

Research fields

Bioprospecting and tailoring of microbial strains, mainly yeasts, for the production of heterologous proteins, fine and bulk chemicals, biofuels, nutraceuticals. Metabolic engineering, flow cytometry, screening protocols for improving key performance indicators are the approaches used to select strains with the desired features, including robustness against stress. The goal is the development of sustainable bioprocesses, where non-edible organic residues can be valorized by microbial fermentation in an integrated biorefinery.

Academic, scientific activities and technology transfer

Lecturer of Industrial Microbiology, Industrial Processes and Biorefineries; Microbiology of the Bachelor Degree in Biotechnology and Biology; director of two PhD programmes, “Biology & Biotechnology” and “Converging Technologies for Biomolecular Systems (TeCSBi)” at the University of Milano-Bicocca.

Delegate of the Department for the KIC Raw Materials “RawMatters”.

She coordinates the IndBioTech lab now supervising 2 post-Docs, 6 PhD students of 2 different PhD programmes, and 4 master students. She is one of the directors of a Summer School in Bio-Based Processes, and teacher in national Master programmes on Circular Bioeconomy and Sustainability.

Publications: over 60 peer-reviewed papers, 7 book chapters.

(Co-)inventor of 9 patent applications, 6 of which obtained the PCT status, and 5 subsequently licensed.

Co-founder and President of the academic spin-off Galatea Bio Tech S.r.l., active in the production of bio-based biodegradable materials.

Principles and concepts of Open Science and RRI are embedded both in her researches as in her teaching and communication activities.

Involvement in Research and Training Programmes 

Prof. Branduardi has participated in several national and EU-funded research and PhD training projects. Among other, the following European FP VII: NEMO (Novel high performance enzymes and micro-organisms for conversion of lignocellulosic biomass to bioethanol); Coordination Actions SYSINBIO (Systems Biology as a Driver for Industrial Biotechnology); Marie Curie ITN YEASTCELL (2013-2017). BIOGESTECA, BIOREFILL and BEETOUT: national projects looking over the production of biofuels and chemicals from renewable biomasses.

Prof. Branduardi is currently beneficiary of the Marie Sklodowska-Curie EJD YEASTDOC (2017-2021) and she is the coordinator of the national research project MYSUSHI (valorisation of crude glycerol into fish feed). She is also involved as PI and as member of the MC of the COST Action CA18113, Understanding and exploiting the impacts of low pH on micro-organisms.


  • Maestroni, L., Butti, P., Senatore, V., Branduardi, P. (2023). pCEC-red: a new vector for easier and faster CRISPR-Cas9 genome editing in Saccharomyces cerevisiae. FEMS YEAST RESEARCH, 23 [10.1093/femsyr/foad002]. Dettaglio

  • Mastella, L., Senatore, V., Beltrani, T., Branduardi, P. (2023). Scheffersomyces stipitis ability to valorize different residual biomasses for vitamin B9 production. MICROBIAL BIOTECHNOLOGY, 16(2 (February 2023)), 392-403 [10.1111/1751-7915.14177]. Dettaglio

  • Maestroni, L., Butti, P., Milanesi, R., Pagliari, S., Campone, L., Serra, I., et al. (2023). Easy Modular Integrative fuSion-ready Expression (Easy-MISE) Toolkit for Fast Engineering of Heterologous Productions in Saccharomyces cerevisiae. ACS SYNTHETIC BIOLOGY, 12(5), 1508-1519 [10.1021/acssynbio.3c00015]. Dettaglio

  • Cannavacciuolo, C., Pagliari, S., Giustra, C., Carabetta, S., GUIDI NISSIM, W., Russo, M., et al. (2023). LC-MS and GC-MS Data Fusion Metabolomics Profiling Coupled with Multivariate Analysis for the Discrimination of Different Parts of Faustrime Fruit and Evaluation of Their Antioxidant Activity. ANTIOXIDANTS, 12(3), 1-17 [10.3390/antiox12030565]. Dettaglio

  • Di Lorenzo, R., Serra, I., Porro, D., Branduardi, P. (2022). State of the Art on the Microbial Production of Industrially Relevant Organic Acids. CATALYSTS, 12(2) [10.3390/catal12020234]. Dettaglio

Progetti di ricerca

AGRO2CIRCULAR - Territorial Circular Systemic Solution for the upcycling of residues from the agrifood sector
Anno: 2021
Bando: Demonstration of systemic solutions for the territorial deployment of the circular economy
Enti finanziatori: EUROPEAN COMMISSION
REPLAY: REconnecting PLAstics life cycle to biogeochemical cycles by sustainable hydrolysis and Yeasts fermentation
Anno: 2021
Bando: Decreto Direttoriale n.1628 del 16-10-2020 - Bando PRIN 2020
KIC - ADMA2 -Practical training between Academia and Industry during doctoral studies
Anno: 2019
Bando: 2017-083 - Call 5 for KAva Education Projects
Enti finanziatori: EIT RAW MATERIALS GMBH
CARDoon valorisation by InteGrAted biorefiNery (CARDIGAN)
Anno: 2017
Bando: PRIN 2017
YEASTDOC - Yeast Biotechnology Doctoral Training Programme
Anno: 2017
Bando: 2016-049 - H2020 - MSCA -ITN-2017, H2020- MSCA-ITN-2017, H2020- MSCA_ITN-2017, H2020-MSCA-ITN-2017, H2020-MSCA_ITN-2017
Enti finanziatori: UNIONE EUROPEA

Premi e responsabilità scientifiche


  • Top Cited Article Award, Elsevier Science, 2013
  • Best Poster Award, ADM, INGEGRAF, PRIMECA, 2004

Partecipazioni scientifiche

  • Componente dell'Executive Commitee - European Federation of Biotechnology (Spagna), 2020
  • Segretario - Microbial Physiology Section - European Federation of Biotechnology (Spagna), 2019
  • Componente del Consiglio/Comitato Direttivo - SIMGBM, Società Italiana di Microbiologia Generale e Biotecnologie Microbiche (Italia), 2016 - 2020
  • Fellow - EFB (European Federation of Biotechnology) (Italia), 2009

Comitati editoriali

  • Direttore di rivista, collana editoriale, enciclopedia - FEMS MICROBIOLOGY LETTERS, 2016 - 2017


  • Program committee - MICROBIAL STRESS from Molecules to Systems 5th edition(Italia), 2020
  • Program committee - Applied Synthetic Biology in Europe V Edition(Paesi Bassi), 2020
  • Program chair - 7ma Conferenza: “Physiology of Yeast and Filamentous Fungi - PYFF” Italia, 2019(Italia), 2019
  • Program committee - Microbial Stress: from systems to molecules and back(Irlanda), 2018
  • Program committee - ISSY33 - Exploring and Engineering Yeasts for Industrial Application(Irlanda), 2017
  • Program chair - Microbial Stress: From Molecules To Systems (3rd edition)(Spagna), 2015
  • Program chair - "MICROBIAL STRESS from Molecules to Systems” Belgirate, Italy (2nd Conference), 2012
  • Program chair - “MICROBIAL STRESS from Molecules to Systems” Semmering, Austria (1st Conference), 2009