NICOLIS SILVIA KIRSTEN

Ruolo:
Professoressa associata
Settore scientifico disciplinare:
Genetica (BIO/18)
Telefono:
Stanza:
  • U03, Piano: 3, Stanza: 3046

Pubblicazioni

  • Mercurio, S., Pozzolini, G., Baldi, R., Barila, S., Pitasi, M., Catona, O., et al. (2023). Hooked Up from a Distance: Charting Genome-Wide Long-Range Interaction Maps in Neural Cells Chromatin to Identify Novel Candidate Genes for Neurodevelopmental Disorders. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24(2) [10.3390/ijms24021164]. Dettaglio

  • Mercurio, S., Serra, L., Pagin, M., Nicolis, S. (2022). Deconstructing Sox2 Function in Brain Development and Disease. CELLS, 11(10) [10.3390/cells11101604]. Dettaglio

  • Li, L., Medina-Menendez, C., Garcia-Corzo, L., Cordoba-Beldad, C., Quiroga, A., Calleja Barca, E., et al. (2022). SoxD genes are required for adult neural stem cell activation. CELL REPORTS, 38(5) [10.1016/j.celrep.2022.110313]. Dettaglio

  • Pagin, M., Pernebrink, M., Giubbolini, S., Barone, C., Sambruni, G., Zhu, Y., et al. (2021). Sox2 controls neural stem cell self-renewal through a Fos-centered gene regulatory network. STEM CELLS, 39(8), 1107-1119 [10.1002/stem.3373]. Dettaglio

  • Pagin, M., Pernebrink, M., Pitasi, M., Malighetti, F., Ngan, C., Ottolenghi, S., et al. (2021). Fos rescues neuronal differentiation of sox2-deleted neural stem cells by genome-wide regulation of common sox2 and ap1(Fos-jun) target genes. CELLS, 10(7) [10.3390/cells10071757]. Dettaglio

Progetti di ricerca

unctional validation of candidate neurodevelopmental disease genes identified via genome-wide association studies (GWAS) analysis of non-coding DNA elements
Anno: 2023
Bando: FAQC 2023 - seconda finestra
Enti finanziatori: Università degli Studi di MILANO-BICOCCA
A CRISPR-Cas9-based high-throughput screen in human brain organoids of T-dark putative downstream effectors of SOX2 in neurodevelopmental disease
Anno: 2022
Enti finanziatori: FONDAZIONE TELETHON, FONDAZIONE CARIPLO
Brain gene regulation in 3D: long-range promoter-enhancer functional interaction networks in mouse and human brain cells, and their relevance for neurodevelopmental disease
Anno: 2021
Bando: FAQC 2021 - prima finestra
Enti finanziatori: Università degli Studi di MILANO-BICOCCA
IMPROVVISION - Understanding and reprogramming developmental visual disorders: from anophthalmia to cortical impairment
Anno: 2016
Bando: 2015-063 - European Research Projects on Neurodevelopmental Disorders
Enti finanziatori: MINISTERO DELLA SALUTE
Linking Sox2 activity to its downstream effectors in glioma maintenance, towards the definition of therapeutic targets - II annualità
Anno: 2016
Bando: 2014-002 - Investigator Grant 2014
Enti finanziatori: FONDAZIONE AIRC PER LA RICERCA SUL CANCRO ETS